Pole. Kama uko Dar Es Salaam nenda pale Manzese Phabek Pharmacy waambie wakupe hii dawa. Amitriptyline, niliwahi kuitumia huko nyuma nililala siku tatu mpaka mwenye nyumba akajua nimevuta... It helps in a number of disorders ila la kukosa usingizi au Insomnia pia linasaidia. Kwa msaada Zaidi google disorder inayoitwa Insomnia...
Amitriptyline as an Insomnia Treatment
Off-Label Use for an Anti-depressant
Amitriptyline is a drug approved for the treatment of depression. However, like
other types of anti-depressants, it’s also commonly used as an off-label treatment for insomnia. Off-label drugs are not FDA approved for alternative uses, but because of relative effectiveness medications like amitriptyline gain new uses in popular medicine.
Besides its alternative use as sleep aid, amitriptyline is also used to treat pain associated with a wide array of medical conditions.
How Amitriptyline Works
Amitriptyline works as an anti-depressant by suppressing serotonin reuptake and norepinephrine uptake, as well. Both serotonin and norepinephrine are important neurotransmitters responsible for automatic mood and body responses. When both are in short supply the symptoms of depression, in tandem often with insomnia, can occur. Amitriptyline is known as a tricyclic antidepressant for its molecular structure.
As a Treatment for Insomnia
Remember, amitriptyline was not designed as a sleep aid, but as an anti-depressant and as such has many more popular anti-depressants ahead of it. But it’s usefulness as a sleep aid continues. Biggest benefit is the drug’s long half-life, 12-24 hours, which far exceeds that of most insomnia medications. This bioavailability makes the drug useful for patients with late waking insomnia—or the propensity for waking very early in the morning, at the end of the sleep cycle, unable to return to sleep.
But as drugs go one of the biggest controversies surrounding the use of amitriptyline is its use among physicians who prescribe it first for insomnia. Interestingly one of the common side effects IS insomnia, along with dry mouth, weight gain, dizziness, and confusion. But the challenge with some more common prescription sleep aids is their super short half-lives, making them totally useless for late insomnia sufferers.
How Amitriptyline is Used as an Off-Label Treatment for Sleep Disturbance