De Bruyne is a Dutch surname meaning "the brown one". The name is variably spelled Debruyne or De Bruijne as well. More common forms are De Bruin, De Bruijn, and De Bruyn.
People with this surname include:
Kevin De Bruyne (born 1991), Belgian footballer
Donatien de Bruyne (1871–1935), French biblical scholar
Fred De Bruyne (1930–1994), Belgian road race cyclist
Gustave De Bruyne (fl. 1920), Belgian long jumper
Hector De Bruyne (1917–1995), Belgian politician
Henri De Bruyne (1868–1892), Belgian Congo Free State sergeant
Kamiel De Bruyne (born 1992), Belgian television producer
Kris De Bruyne (1950–2021), Belgian singer
Mattheus de Bruyne (1895–1973), Dutch military leader
Norman de Bruyne (1904–1997), British aircraft engineer and industrialist
Pierre De Bruyne (1905–?), Belgian cyclist
Rykel de Bruyne, Dutch malacologist
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