Glucuronolactone is a naturally occurring chemical that is an important structural component of nearly all connective tissues.Glucuronolactone is also found in many plant gums.
Glucuronolactone is a white solid odorless compound, soluble in hot and cold water. Its melting point ranges from 172°C (341.6°F) to 175 C° (347 °F). The compound can exist as non-cyclic aldehyde or as cyclic hemiacetal ("lactol") form.
Lactol form of Glucuronolactone
It has received some notoriety due to urban legends that it was a Vietnam War-era drug manufactured by the American government.
The rumor goes on to say that it was banned due to several brain tumor-related deaths.
The rumor has since been proven false, as neither the cited British Medical Journal article nor the "banning of its consumption" ever occurred. Furthermore, no warnings appear on the Food and Drug Administration website regarding its potential to cause brain tumors or other maladies.
Glucuronolactone is rapidly absorbed and metabolised into non-toxic metabolites such as xylulose. In addition, humans may be able to use glucuronolactone as a precursor for ascorbic acid synthesis.[3] According to "The Merck Index", it is also used as a detoxicant.[4]
Glucuronolactone is a popular ingredient in energy drinks with claims that it detoxifies the body. Although levels of glucuronolactone in energy drinks can far exceed those found in the rest of the diet, the European Food Safety Authority (EFSA) has concluded that exposure to glucuronolactone from regular consumption of energy drinks is not a safety concern (No Observed Adverse Effect Level of glucuronolactone = 1,000mg/kg/day).
Glucuronolactone - Wikipedia, the free encyclopedia
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