V.V.U na Upimaji wake (Coincidences)

V.V.U na Upimaji wake (Coincidences)

DAVIES said:
Naomba nikupe assignment kwanza please kabla ya majibu yako naomba tafuta true definition ya antigen na antibody halafu naomba pitia lymphocytes kwanza ujue umuhimu wake na zina fanyaje kazi types zake pia halafu functions na uangalie Hiv life cycle shortly nikipata tyme nitaanza discusion na wewe kuanzia qstn 1 hapo
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Hii thread umeipitia yote from page one mpaka mwisho?

-Kaveli-
 
kauzu12 said:
[emoji3] [emoji3] [emoji3] [emoji3] mkuu kaveli huyu katoka usingizini tumpuuze.
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Hahaha mkuu, naona jamaa kaja moto kweli na 'assignment'. Hajuwi kuwa hiyo assignment aliyonipa, wajuvi wa mambo tayari weshacheza nayo sana humu.

Na nahisi hajasoma hata robo ya uzi huu.

-Kaveli-
 
Kaveli said:
Hahaha mkuu, naona jamaa kaja moto kweli na 'assignment'. Hajuwi kuwa hiyo assignment aliyonipa, wajuvi wa mambo tayari weshacheza nayo sana humu.

Na nahisi hajasoma hata robo ya uzi huu.

-Kaveli-
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Hahahaha unacheza pata potea nimemwambia asome kwanza awe na idea ili nije nianze kujibu kwanini hiv tuna detect antibodies huwezi uliza antibodies while you know nothing about it nimegusia lymphocytes kwasababu ndizo zinatengeneza antibodies ok mi sio kichaa kavel na deal na hayo mambo asee sijatoka usingizini wala sijakurupuka nimempa apate idea so nilitegemea atakuja na jibu tuanze swali la kwanza mpk la mwisho ila poa nitatoa majibu sio issue ok
 
kauzu12 said:
[emoji3] [emoji3] [emoji3] [emoji3] mkuu kaveli huyu katoka usingizini tumpuuze.
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Asee sijatoka usingizini kwanza naomba utambue nimemwambia muhusika asome japo apate idea ili nitakapogusia hayo mambo awe anaelewa kidogo hiv nina deal nae kijana sema ina elimu ndefu na inahitaji kuwa na uelewa wa terms ambazo zitatumika ila poa nitatoa majibu soon ili mjue nimesoma uzi wote ok
 
DAVIES said:
Asee sijatoka usingizini kwanza naomba utambue nimemwambia muhusika asome japo apate idea ili nitakapogusia hayo mambo awe anaelewa kidogo hiv nina deal nae kijana sema ina elimu ndefu na inahitaji kuwa na uelewa wa terms ambazo zitatumika ila poa nitatoa majibu soon ili mjue nimesoma uzi wote ok
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Sawa mkuu. tuletee huo uzi tuusome
 
Kaveli said:
Wakuu,
With due respect ta all of you.

Ever since the existence of HIV/AIDS in our lovely planet, there are some concerns that always crack my mind, and I really get puzzled! Ni kuhusu hizi HIV-Testing Kits as regards to HIV diagnosis in human bodies. Napenda sana kujifunza vitu mbali mbali, hususani issues zinazo-impact afya zetu wanadamu.

To whoever mwenye uelewa, naomba mnieleweshe (na kwa faida ya wengine pia) kwenye mambo yafuatayo ili kujifunza:

a) Je vifaa vyote vya kupimia HIV, vinatumia ''ANTIBODIES'' pekee ili kudetect HIV infections ktk mwili? Yaani is 'ANTIBODIES'' only the determinant/agent for confirmation of HIV presence in the body?

b) If YES to the (a) above, why hivyo vifaa haviwezi kudetect the HIV directly? i.e. why hivyo vipimo (HIV-Testing) haviwezi kutrace (to isolate) the Virus itself, rather than basing on the antibodies? OR ni kwa sababu kwamba all virus-related infections can be only detected by basing on antibodies only?

c) Uelewa wangu mdogo ni kwamba Human Beings tuna natural Immunity Systems kwenye miili yetu, and the primary role of such natural immunity ni kuproduce 'antibodies' to fight-off a disease infection(s) that enters the body. The strength of such Immunity varies from person to person, due to nutrition factors; life style; etc. Pia nafahamu kwamba wanadamu tuna a lot of viruses and bacteria kwenye miili yetu, though hatuugui. Mfano, niliwahi kusoma a medical Article kwamba almost kila mtu ana bacteria wa TB mwilini mwake, whenever your body Immunity becomes weak, ndo hapo unaanza kuugua TB. So all viruses or bacterias or whatever harm in the body... they do primarily depend on vulnerability of the body Immunity. Nadhania hivyo.

Now the question is: Immunity huwa inaproduce izo 'antibodies' to ALL disease infectios that enter the body?? i.e. does the Immunity System react and produce antibodies to ANY/ALL infections? OR kuna baadhi tu ya diseases/infections ambazo ndo Immunity ina-react na kutoa antibodies??

d) If the body Immunity reacts and/or produces the 'antibodies' to ANY/ALL disease infections, do the 'antibodies' differ from infection to infection? Yaani mfano: antibodies for Ebola infections are different from antibodies for HIV infections??

e) If NO to the (d) above, then it means that the allegedly produced 'antibodies' are of ONE TYPE (ONE STRUCTURE) WITH SAME FEATURES, WITH SAME PARTICLES, for ANY/ALL disease infections in the body. Now... WHY is HIV-diagnosis being based on 'antibodies' only, while other disease infections are also an avenue for the 'same antibodies' in the body???

(f) Pia kuna hizi medical terminologies: CD4 COUNT; na ''VIRAL LOAD''.
Navyoelewa mimi, viral load ni kile kiasi cha viruses mwilini, yani kiwango cha virusi kwenye damu. SWALI: Hicho kipimo cha viral load, je kinapima na kutoa matokeo ya kiwango cha virusi wote kwa ujumla (bila kujali aina ya kirusi) waliopo kwenye damu? ama kinapima na kutoa matokeo in isolation kwa kila aina ya kirusi kwenye damu??

Karibuni waungwana. Let's double-click our folders of thinking and share knowledge.

I humbly submit, and thanks in advance for reading.
N.B: I stand to be corrected!
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swali refu mpka unaeza ukasahau points of view,
anyways nitajaribu juzungumza kwa kile ninachokifahamu kuhusu hayo makitu
a) sio kweli vifaa vyote vinatumia antibodies isipokua tu vile vya serological tu ndo ambavyo vifanya kazi na kutoa majibu kwa reaction ya antibodies na antigen.na vinasifa ya kua cheap,no need of highly proffesiona skills,takes less time.
viko vingi kama UPT vile vya mimba, MRDT vile vya malaria n.k
b)serological test haziwezi ku isolate a virus directly jappo vipo vipimo vingine kama PCR- Polymarase chain reaction ambacho kinaweza kuisolate DNA of a virus from a sample na hivyo ku detect vurus.
c) There number of ways by which our bodies responds to foreign bodies not only infections, basing on the question nikua if our immunity system is strong enough then our bodies are free from diseases since our immunity system will be able to deffend the body and get rid of all i call foreign bodies-bacterias,virus,fungus n.k
if our immunity system is weak the any disease may get into our bodies without any resistance.
Under normal circumstances antibodies works in the lock and key system,thats they are very specific kwa antigen ilionekana yaani mdudu akiingia mwilini mwili ukamdetect unamfanyia kitu kama scaning ya kumjua vizuri mdudu huyo then zinatengenezwa cells(antibodies) specifically kwa ajili ya kumuua mdudu husika tu na akisha uliwa zile cell zinakua useless ila huwa kuna memory inabaki next time akirudi huyo mdudu its just a reactivation of the antibodies then anashughhulikiwa faster.
CD4-Cellular differentiation 4. hizi ni cell za mwili ambazo hufanya kazi ya kuspot yaaani hutoa taarifa za mdudu alieingia ili ashughulikiwe,zipo CD8 hizi huitwa pia Natural killer cells zenyewe zinafigh na kwaida CD4 huwa nyingi zaidi ya CD8 japo kuna watu wenye anomaly ambao CD8 ni nyingi zidi na hivyo huwa hawapati magonjwa sana. Back to question HIV huwa anashikizwa na structures za cells za CD4 zinazojulikana CXR4 na XXR5 kama sijazichanganya , na baada ya hapo virus anapata access ya kuingia ndani ya iyo cell na kufanya replication ya kutosha then cell hiyo ya CD4 inakufa ndo maana CD4 huwa zinapungua. sina uhakika sana na Viral load but nahisi pia ni specific pia.

naomba kuwasilisha wakuuu
 
Milipede said:
swali refu mpka unaeza ukasahau points of view,
anyways nitajaribu juzungumza kwa kile ninachokifahamu kuhusu hayo makitu
a) sio kweli vifaa vyote vinatumia antibodies isipokua tu vile vya serological tu ndo ambavyo vifanya kazi na kutoa majibu kwa reaction ya antibodies na antigen.na vinasifa ya kua cheap,no need of highly proffesiona skills,takes less time.
viko vingi kama UPT vile vya mimba, MRDT vile vya malaria n.k
b)serological test haziwezi ku isolate a virus directly jappo vipo vipimo vingine kama PCR- Polymarase chain reaction ambacho kinaweza kuisolate DNA of a virus from a sample na hivyo ku detect vurus.
c) There number of ways by which our bodies responds to foreign bodies not only infections, basing on the question nikua if our immunity system is strong enough then our bodies are free from diseases since our immunity system will be able to deffend the body and get rid of all i call foreign bodies-bacterias,virus,fungus n.k
if our immunity system is weak the any disease may get into our bodies without any resistance.
Under normal circumstances antibodies works in the lock and key system,thats they are very specific kwa antigen ilionekana yaani mdudu akiingia mwilini mwili ukamdetect unamfanyia kitu kama scaning ya kumjua vizuri mdudu huyo then zinatengenezwa cells(antibodies) specifically kwa ajili ya kumuua mdudu husika tu na akisha uliwa zile cell zinakua useless ila huwa kuna memory inabaki next time akirudi huyo mdudu its just a reactivation of the antibodies then anashughhulikiwa faster.
CD4-Cellular differentiation 4. hizi ni cell za mwili ambazo hufanya kazi ya kuspot yaaani hutoa taarifa za mdudu alieingia ili ashughulikiwe,zipo CD8 hizi huitwa pia Natural killer cells zenyewe zinafigh na kwaida CD4 huwa nyingi zaidi ya CD8 japo kuna watu wenye anomaly ambao CD8 ni nyingi zidi na hivyo huwa hawapati magonjwa sana. Back to question HIV huwa anashikizwa na structures za cells za CD4 zinazojulikana CXR4 na XXR5 kama sijazichanganya , na baada ya hapo virus anapata access ya kuingia ndani ya iyo cell na kufanya replication ya kutosha then cell hiyo ya CD4 inakufa ndo maana CD4 huwa zinapungua. sina uhakika sana na Viral load but nahisi pia ni specific pia.

naomba kuwasilisha wakuuu
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Ahsante mkuu kwa mchango wako kwenye uzi huu. Mie naomba nikuulize mambo mawili tu kwenye hayo maelezo yako...

Hapo kwenye (b): Je unamfahamu mgunduzi wa hicho kipimo PCR? Je mgunduzi huyo wa PCR anasemaje kuhusu hypothesis ya HIV/AIDS?

Hapo kwenye (c): nakunukuu "if our immunity system is strong enough then our bodies are free from diseases since our immunity system will be able to deffend the body and get rid of all i call foreign bodies-bacterias,virus,fungus n.k... "
So mtu mwenye enough strong immune system can naturally kill and get rid of HIV?

-Kaveli-
 
DAVIES said:
Hahahaha unacheza pata potea nimemwambia asome kwanza awe na idea ili nije nianze kujibu kwanini hiv tuna detect antibodies huwezi uliza antibodies while you know nothing about it nimegusia lymphocytes kwasababu ndizo zinatengeneza antibodies ok mi sio kichaa kavel na deal na hayo mambo asee sijatoka usingizini wala sijakurupuka nimempa apate idea so nilitegemea atakuja na jibu tuanze swali la kwanza mpk la mwisho ila poa nitatoa majibu sio issue ok
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"...huwezi uliza antibodies while you know nothing about it... ".
So mtu kuuliza jambo ni mpaka kwanza awe na idea nalo? Ni nini sasa essence ya kuuliza?
Wewe ni mtaalam gani ambaye huwezi kumuelezea jambo layman kwa lugha rahisi akaelewa?
Unapata uvivu kwenye fani yako. Pole sana dokta.

-Kaveli-
 
Kaveli said:
Ahsante mkuu kwa mchango wako kwenye uzi huu. Mie naomba nikuulize mambo mawili tu kwenye hayo maelezo yako...

Hapo kwenye (b): Je unamfahamu mgunduzi wa hicho kipimo PCR? Je mgunduzi huyo wa PCR anasemaje kuhusu hypothesis ya HIV/AIDS?

Hapo kwenye (c): nakunukuu "if our immunity system is strong enough then our bodies are free from diseases since our immunity system will be able to deffend the body and get rid of all i call foreign bodies-bacterias,virus,fungus n.k... "
So mtu mwenye enough strong immune system can naturally kill and get rid of HIV?

-Kaveli-
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Mgunduzi wa hiyo PCR kiukweli simjui japo niliona video fulani ivi na sikuitilia maanani.
No hawezi ku resist, the reason nikua Virus has the higher ability to replicate.Once virus has entered our body particularly HIV they quickly undergo Geneticall transcription whereby hiv is RNA and human genome is DNA so the virus quickly changes to RNA DNA double stranded then inakua DNA double stranded na kisha inajishikisha kwenye DNA za mtu na inaanza kutengeneza viral parts from human genetical make up as it is then containig viral part. kumbuka wakati kirusi kinaingia kilikua ni RNA sooo antbodies zilitengenezwa specifically kwaajili ya RNA ambapo kimeshabadilika nakua RNA DNA double stranded tena recruitment of fighter cells inafanyika specifically kwaajili yaRNA DNA ambapo tiari anakua amebadilika na kua DNA Double stranded............soooo the only thing kinachoweza kufanyika hali ya resistance kwa hiv ni kukosekana kwa zile structures za aattachment kwenye CD4 cells CXR4 NA XXR5.

NI MTAZAMO WANGU HUO MWENYE ZAIDI NA ALETE TUJADILI
 
Dola Iddy said:
Nimeshindwa kuielewa lugha yako manake unachanganya kiingereza na kiswahili.
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Katika lugha yeyote ile duniani, 'code mixing' sio dhambi.

Hata hivyo, sio lazima kila mtu aelewe. Waachie wanaoelewa.

-Kaveli-
 
Kaveli said:
Katika lugha yeyote ile duniani, 'code mixing' sio dhambi.

Hata hivyo, sio lazima kila mtu aelewe. Waachie wanaoelewa.

-Kaveli-
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Hata hapa sijakuelewa kwa kweli jaribu kutumia lugha moja pekee , kama mimi ninavyoandika hapa sichanganyi na lugha ya kiingereza wala kifaransa na ndio maana katika vitabu maalumu vya masomo huwezi kukuta kitu cha namna hiyo , jaribu tena kunielewesha juu ya ujumbe uliandika hapo juu kwa lugha moja pekee.
 
Dola Iddy said:
Hata hapa sijakuelewa kwa kweli jaribu kutumia lugha moja pekee , kama mimi ninavyoandika hapa sichanganyi na lugha ya kiingereza wala kifaransa na ndio maana katika vitabu maalumu vya masomo huwezi kukuta kitu cha namna hiyo , jaribu tena kunielewesha juu ya ujumbe uliandika hapo juu kwa lugha moja pekee.
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Sio lazima uelewe kila ukisomacho. Waachie wanaoelewa.

-Kaveli-
 
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