Dawa ya ukimwi; Njia za kutengeneza dawa ya ukimwi huu ni mtizamo wangu

[Dennis Robert Shughuru]

Nikiwa Rais ntaanzisha mchakato wa kutengeneza dawa ya ukimwi
👇👇👇👇👇
How potential HIV drug will work
it engulf viral RNA genome which is essential for viral life and eliminate it.

HIV viral structure

Desired therapeutics method;- engulf viral RNA genome and eliminated it

Method of developing HIV drug

• Predict viral docking glycoprotein, matrix protein, transmembrane glycoprotein, and capsid mutation cycles
• Integrate mutation cycles into one model
• Find chemical from nature which can be able to pass docking glycoprotein, transmembrane glycoprotein and capsid protein compound model and engulf viral RNA
• Pre Clinical trial
• Clinical trial
• Approval

Strength of the drug

• Even the viral undergo mutation the drug efficacy will remain the same and not wane.

 

[Dennis Robert Shughuru]

Kwa ambao hamjui njia za kutengeneza dawa nimeelezea kwenye huu uzi

Zifahamu njia zitumikazo kutengeneza hizi dawa zinazouzwa pharmacy

Nikiwa Rais wa Tanzania kutakua na mpango wa kuzalisha dawa hapa Tanzania, je wajua njia za kutengeneza dawa??? Zifuatazo ni njia za kutengeneza dawa Kama nchi tutategeneze library kubwa itakayokuwa na chemical or compound zinazopatika kwenye nature na zinaposes unique features kama;- ENGULF...

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[Leejay49]

Hivi mwashimiwa una mpango wa kugombea mwaka huu au 2030??

 

[Dennis Robert Shughuru]

Hivi mwashimiwa una mpango wa kugombea mwaka huu au 2030??

Kuanzia mwaka huu 2025 nipo kwenye kinyanganyiro ch Urais wa Tanzania

 

[Leejay49]

Kuanzia mwaka huu 2025 nipo kwenye kinyanganyiro ch Urais wa Tanzania

Chama gani??

 

[Dennis Robert Shughuru]

Chama gani??

Sina chama

 

[Odense]

Sina chama

Kwann

 

[lost files]

Sina chama

Karibu Chaumma mkuu

 

[Ibilisi Mjalaana]

Hv ni vichekesho, lkn dawa rahisi ya kutopata ukimwi ni kutokua na Kinga ya mwili sana CD4 kweny white blood cells!!! Swali je inawezekana kuzitoa na madhara yapoje?

 

[Nomadiq]

Waziri wa Afya ya akili Mhe. min -me njoo utoe taarifa.

 

[Dennis Robert Shughuru]

Hv ni vichekesho, lkn dawa rahisi ya kutopata ukimwi ni kutokua na Kinga ya mwili sana CD4 kweny white blood cells!!! Swali je inawezekana kuzitoa na madhara yapoje?

Kama unasema ni vichekesho basi uwezo wako ni mdogo juu ya haya mambo sio kosa lako

 

[Dennis Robert Shughuru]

Karibu Chaumma mkuu

Nop

 

[Ibilisi Mjalaana]

Kama unasema ni vichekesho basi uwezo wako ni mdogo juu ya haya mambo sio kosa lako

Nina uwezo mpana kukizidi kweny hiyo kada, lkn skupingi ww kua raisi maana hakuna anaejua vyote

 

[Ibilisi Mjalaana]

Kubadili muundo wa CD 4 receptors ndo njia kubwa lkn madhara n mengi kuliko faida, kutokua kabsa na CD 4 receptors ndo jibu la moja Kwa Moja lakn hapo utakufa hata Kwa fangasi wa kweny pumbu, kufunga lango la pili la CD 4 receptors ndo njia YENYE mafanikio hadi sasa lkn napo inaathiri ufanyaji kazi wa Kinga za mwili.

Mwisho kabsa tuombe mungu miili yetu evolve yenyewe kutengeneza natural antibodies za kupambana na huu ugonjwa lakn kitaaluma hadi sasa tumeshindwa lakn jitihada zinaendelea na hakuna kukata tamaa

 

[Dennis Robert Shughuru]

Nina uwezo mpana kukizidi kweny hiyo kada, lkn skupingi ww kua raisi maana hakuna anaejua vyote

Kama ungekuwa na uwezo mkubwa kwenye dawa basi ungejulikana fahamu hakuna kampuni yeyote ya afrika iliyozalisha dawa

South africa angalau wanafanya attempt sababu ya wale wazungu

Mimi nina mambo ambayo hata wazingu hawayajui mfano
Hakuna mtu ameshawahi kuwaza kupredict protein mutation

Hakuna mtu duniani ambaye anajua rules behind amino acids sequence which make protein ila mimi naijua hiyo rule

Hakuna mtu duniani anajua protein folding mechanism ila mimi ninajua protein folding mechanism

 

[Ibilisi Mjalaana]

Kama ungekuwa na uwezo mkubwa kwenye dawa basi ungejulikana fahamu hakuna kampuni yeyote ya afrika iliyozalisha dawa

South africa angalau wanafanya attempt sababu ya wale wazungu

Mimi nina mambo ambayo hata wazingu hawayajui mfano
Hakuna mtu ameshawahi kuwaza kupredict protein mutation

Hakuna mtu duniani ambaye anajua rules behind amino acids sequence which make protein ila mimi naijua hiyo rule

Hakuna mtu duniani anajua protein folding mechanism ila mimi ninajua protein folding mechanism

Mkuu hakuna kitu kipya kwasasa kwahyo usiseme hakuna anaejua, Dunia ya sasa ni innovation tu hakuna mambo ya uvumbuz

 

[Dennis Robert Shughuru]

Kubadili muundo wa CD 4 receptors ndo njia kubwa lkn madhara n mengi kuliko faida, kutokua kabsa na CD 4 receptors ndo jibu la moja Kwa Moja lakn hapo utakufa hata Kwa fangasi wa kweny pumbu, kufunga lango la pili la CD 4 receptors ndo njia YENYE mafanikio hadi sasa lkn napo inaathiri ufanyaji kazi wa Kinga za mwili.

Mwisho kabsa tuombe mungu miili yetu evolve yenyewe kutengeneza natural antibodies za kupambana na huu ugonjwa lakn kitaaluma hadi sasa tumeshindwa lakn jitihada zinaendelea na hakuna kukata tamaa

Tatizo la viral hasa RNA viral ni kwamba protein ku-undergo mutation hiyo ndo kikwazo kikubwa sana na ukienda hata kwenye cancerous cells utakutana na hii changamoto protein wana-undergo mutation constant

Ukitengeneza dawa leo ikakamilika hujamaliza viral ame-undergo mutation kwa hiyo dawa yako inakua imepungua efficacy

Chanagmoto sio hayo uliyoyaandika bali ni kudeal na protein

 

[Dennis Robert Shughuru]

Mkuu hakuna kitu kipya kwasasa kwahyo usiseme hakuna anaejua, Dunia ya sasa ni innovation tu hakuna mambo ya uvumbuz

Hakuna mtu yeyote duniani mpaka navyoandika sahivi anayeweza kupredict protein mutation, hakuna mtu dunia anayejua amino acids sequence rules ambazo zina make protein

Kama haya mambo ya protein huyajui basi bado kuna mambo mengi hujui

 

[Silas Samuel]

Sina chama

Sasa kam huna chama unachaguliwa na nan,?

 

[Dennis Robert Shughuru]

Mkuu hakuna kitu kipya kwasasa kwahyo usiseme hakuna anaejua, Dunia ya sasa ni innovation tu hakuna mambo ya uvumbuz

Angalia huku nimeelezea protein

Kutakua na mradi kubwa sana wa ku-analyze protein data zote ambazo zipo kwenye uniprot database

Analysis of protein data itabase kwenye maeneo yafuatayo Energy distribution of individual amino acid and complete protein Magnetic force of individual amino acid and complete protein Amino acids sequence rules Protein folding mechanism Predict protein mutation Link ifuatayo inakuonyesha data...

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